Using Oxford-RCGP RSC for observational studies

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Using Oxford-RCGP RSC for observational studies

The Oxford-RCGP RSC has a current membership of over 1600 general practices in England covering approximately 8 million patients who are broadly representative of the English general population. The emergent COVID-19 pandemic has seen a rapid increase in the number of new practices joining the network to support the national surveillance program. The Oxford-RCGP RSC team transforms routine clinical data from individual patient records at practice level into an accessible repository of data for health research. Data is transformed to series of themed datasets readily available research. These datasets include standard RSC population configuration (based on age band, ethnicity, index of multiple deprivation, and rurality), clinical case definitions (generally ontological), covariates, and outcomes. These are benchmarked to ONS standard populations to enable rapid comparisons between the study and national populations.

How to access RCGP RSC data

RCGP RSC data is available for researchers interested in conducting primary care/ linked data studies. To work with us, please download and complete the data request form (below) and email  to MedicalDirectorRSC@rcgp.org.uk.

We would also need :

  • a protocol, clearly defining the purpose of the request and use of data
  • a list of variables (no abbreviations for the medical terms)
  • ethics approval (evidence if such is not needed – for what evidence you can present, please refer to the guidance notes on the form).

Once processed the request is assigned a reference number and added to the log. It is then scheduled for consideration at the weekly technical meeting and monthly RSC Operational meeting. The official approval happens at the fourth Wednesday of each month when the RCGP RSC operational meeting is held.

    Data request form

    Oxford-RCGP RSC Theme datasets

    The Oxford-RCGP RSC team is developing a series of themed datasets that will allow researchers rapid access to theme specific datasets that can be used for research studies. We offer standard protocols that can be modified to cater to the needs of specific research studies. These datasets can be linked to other data sources and prepared according a data structure that fits the analytical requirements of  the proposed study.

    Our currently planned themes (at different stages of development) are given below. Explore our theme datasets which are ready for research studies by clicking on the buttons on the right.

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    How we develop phenotypes and ontologies to support theme datasets
    We start theme development by forming a group of theme experts led by a theme lead. The theme lead will design the theme dataset based on the common requirements for the research theme. The theme lead populates a theme template based on expert knowledge (or study requirement, if the theme is initially focused on producing a dataset for a study). The theme lead then works with a team of code curators to convert the data requirements of a in to a clinical code specification. This is carried out as a two stage approach (click on the links on the right to learn more). The outputs of the code curation process are stored in a code repository in the secure environment. The codes committed to the code repository are immediately available to be used for data extraction. The code repository is capable of updating automatically to reflect to most code changes in future SNOMED CT releases.
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    Systems involved in the theme development process
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    SNOMED CT Code Tool

    Theme leads and clinicians (with expertise in the theme)  use the SNOMED CT code tool developed by the Oxford-RCGP RSC team to curate variables/codes within each theme.

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    Cardiovascular & Diabetes Theme

    General inclusions/exclusions and population covariates:

    • People will be included in cohorts who have a least one year’s historic data in their records.
    • Age will be represented as year or birth
    • Ethnicity will be listed in five categories (we can conduct multiple imputation for missing data)
    • IMD provided at LSOA level to individual records, derived from postcode. Where missing we substitute the practice cohort. Plus provided in quintiles (quintile 1 most deprived)
    • Household size (N.B. Relies on identical address & registered with same practice)
    • Urban, town and city, conurbation (ONS population density)
    • NHS Region – North, Midlands and East, South and London.
    • Registration will be full registration and not include temporary residents
    • We will include a practice indicator
    • We will exclude records where: no valid age or gender, no agreement to share data (approx. 0.2%)
    CVD Theme Template(Nexus 365 access required)
    IDCategoryVariableAvailable for extraction?
    95Chronic Kidney Disease
    100Body Mass Index
    105Height
    110Weight
    1008Asthma
    1500eGFR
    1501PlateletCount
    1502BMI Category: normal
    1503BMI Category: obese
    1504BMICategory: overweight
    1505BMI Category: severe obesity
    1506COVID19: Hospital Discharge
    1507COVID-19: Hospitalisation
    1508COVID-19: Mechanical Ventilation
    1509COVID-19: Supplementary oxygen therapy
    1510COVID-19: Admission to Intensive Care Unit
    1511CRP: elevated
    1512CRP: normal
    1513CRP: numeric
    1514ALT
    1515AST
    1516DMARD
    1517Anticoagulant Monitoring
    1518INR Monitoring
    1519COVID-19: shielded
    1520Temperature
    1521Fever
    1522HbA1c: IFCC
    1523HbA1c: DCCT
    1524HbA1c: Unspecified
    1525Peripheral Vascular Disease: leg
    1526Chronic Lung Disease
    1614Diagnosis based on Death Certificate -Autopsy
    2008Haemorrhagic Stroke
    2010Hypertension
    2011Ischaemic Stroke
    2018Acute MyocardialInfarction
    2021Angina
    2025AtrialFibrillation
    2031Congestive Cardiac Failure
    2041Rheumatoid Arthritis
    2044TIA
    2045Unstable Angina
    2046Random Blood Glucose
    2047Diabetes T1
    2048Diabetes T2
    2049Fasting Blood Glucose
    2050HbA1c
    2051Blood Pressure - Both
    2052Blood Pressure - Diastolic
    2053Blood Pressure - Systolic
    2054HDL cholesterol
    2055LDL cholesterol
    2056Total cholesterol
    2064AsthmaDiagnosis
    2065ActiveSmoker
    2066Ex-smoker
    2067Non-Smoker
    2126COPD ProcessOfCare
    2133COPD Diagnosis
    2144ACR
    2147Chronic Kidney Disease - Stages 3 to 5
    2148Creatinine
    2149PCR

    Cancer Theme

    General inclusions/exclusions and population covariates:

    • People will be included in cohorts who have a least one year’s historic data in their records.
    • Age will be represented as year or birth
    • Ethnicity will be listed in five categories (we can conduct multiple imputation for missing data)
    • IMD provided at LSOA level to individual records, derived from postcode. Where missing we substitute the practice cohort. Plus provided in quintiles (quintile 1 most deprived)
    • Household size (N.B. Relies on identical address & registered with same practice)
    • Urban, town and city, conurbation (ONS population density)
    • NHS Region – North, Midlands and East, South and London.
    • Registration will be full registration and not include temporary residents
    • We will include a practice indicator
    • We will exclude records where: no valid age or gender, no agreement to share data (approx. 0.2%)
    Cancer Theme Template(Nexus 365 access required)
    IDCategoryVariableAvailable for extraction?
    100Body Mass Index
    105Height
    110Weight
    1501PlateletCount
    1502BMI Category: normal
    1503BMI Category: obese
    1504BMICategory: overweight
    1505BMI Category: severe obesity
    1506COVID19: Hospital Discharge
    1507COVID-19: Hospitalisation
    1508COVID-19: Mechanical Ventilation
    1509COVID-19: Supplementary oxygen therapy
    1510COVID-19: Admission to Intensive Care Unit
    1511CRP: elevated
    1512CRP: normal
    1513CRP: numeric
    1514ALT
    1515AST
    1519COVID-19: shielded
    1520Temperature
    1521Fever
    1527Cancer groups: cervical InSitu
    1528Cancer groups: cervical_total
    1529Cancer groups: colon_InSitu
    1530Cancer groups: colon_total
    1531Cancer groups: melanoma_InSitu
    1532Cancer groups: myeloma_MGUS
    1533Cancer groups: oesophagus_Barretts_InSitu
    1534Cancer groups: oesophagus_total
    1535Cancer groups: pancreas_InSitu
    1536Cancer groups: pancreas_total
    1537Cancer groups: stomach_InSitu
    1538Cancer groups: stomach_total
    1539Cancer symptom: postmenopausal_bleeding
    1540Cancer symptom: vaginaldischarge
    1541Cancer referrals (2 week wait): urol
    1542Cancer referrals (2 week wait): UpperGI
    1543Cancer referrals (2 week wait): Skin
    1544Cancer referrals (2 week wait): Sarcoma
    1545Cancer referrals (2 week wait): Lung
    1546Cancer referrals (2 week wait): HeadNeck
    1547Cancer referrals (2 week wait): HaemMalig
    1548Cancer referrals (2 week wait): Gynae
    1549Cancer referrals (2 week wait): Colorectal
    1550Cancer referrals (2 week wait): Breast
    1551Cancer referrals (2 week wait): LowerGI
    1552Cancer referrals (2 week wait): Braincancer
    1553Cancer groups: bladder_InSitu
    1554Cancer groups: bladder_Total
    1555Cancer groups: prostateCa_InSitu
    1556Cancer groups: prostateCa_Total
    1557Cancer groups: prostateCa_Primary
    1558Cancer groups: ovarian_total
    1559Cancer groups: endometrial_InSitu
    1560Cancer groups: endometrial_total
    1561Cancer groups: renal_InSitu
    1562Cancer symptom: Test_Scrotum_Pain
    1563Cancer groups: renal_Total
    1564Cancer symptom: Test_Scrotum_Mass
    1565Cancer symptom: NonCardiac_Chest_Pain
    1566Cancer symptom: UrinaryUrgency
    1567Cancer symptom: UrinaryFrequency
    1568Cancer symptom: Nocturia
    1569Cancer symptom: Retention
    1570Cancer groups: TNM category - In Situ
    1571Cancer symptom: ChangeBowelHabit
    1572Cancer groups: FIGO_Stage4
    1573Cancer groups: FIGO_Stage3
    1574Cancer groups: FIGO_Stage2
    1575Cancer groups: FIGO_Stage1
    1576Cancer groups: _Stage_M1
    1577Cancer groups: _Stage_M0
    1578Cancer groups: _Stage_T4
    1579Cancer groups: _Stage_T3
    1580Cancer groups: _Stage_T2
    1581Cancer groups: _Stage_T1
    1582Cancer groups: Stage_N4
    1583Cancer groups: Stage_N3
    1584Cancer groups: Stage_N2
    1585Cancer groups: Stage_N1
    1586Cancer groups: Stage_N0
    1587Cancer groups: Dukes_A
    1588Cancer groups: Dukes_B
    1589Cancer groups: Dukes_C
    1590Cancer groups: Dukes_D
    1591Cancer groups: breast_InSitu
    1592Cancer groups: breast_Total
    1593Cancer groups: lung_InSitu
    1594Cancer groups: lung_Total
    1595Cancer symptom: breast_SkinNippleChanges
    1596Cancer symptom: breast_Pain
    1597Cancer symptom: UrinaryTractInfection
    1598Cancer groups: anal_Total
    1599Cancer groups: Bone_Total
    1600Cancer groups: penis_total
    1601Cancer groups: hepato_InSitu
    1602Cancer groups: hepato_Total
    1603Cancer groups: Leukaemia_Other
    1604Cancer groups: Leukaemia_Total_Overarching
    1605Cancer groups: Leukaemia_CLL
    1606Cancer groups: Leukaemia_CML
    1607Cancer groups: Leukaemia_ALL
    1608Cancer groups: Leukaemia_AML
    1609Cancer groups: NonHodgkinsLymphoma
    1610Cancer groups: HodgkinsLymphoma
    1611Cancer groups: SpermaticCord_Total
    1612Cancer groups: testicular_InSitu
    1613Cancer groups: testicular_Total
    1614Diagnosis based on Death Certificate -Autopsy
    1615Cancer referrals (2 week wait): AllCancers_seen
    1616Cancer referrals (2 week wait): Urological_seen
    1617Cancer referrals (2 week wait): UpperGI_seen
    1618Cancer referrals (2 week wait): Skin_seen
    1619Cancer referrals (2 week wait): Sarcoma_seen
    1620Cancer referrals (2 week wait): Lung_seen
    1621Cancer referrals (2 week wait): HaemMalig_seen
    1622Cancer referrals (2 week wait): Gynae_seen
    1623Cancer referrals (2 week wait): ColoRectal_seen
    1624Cancer referrals (2 week wait): Breast_seen
    1625Cancer referrals (2 week wait): BrainCancer_seen
    1626Cancer referrals (2 week wait): HeadNeck_seen
    1627Cancer groups: gallbladder_InSitu
    1628Cancer groups: gallbladder_Total
    1629Cancer groups: peritoneum_Total
    2008Haemorrhagic Stroke
    2011Ischaemic Stroke
    2018Acute MyocardialInfarction
    3000Cancer: Referrals
    3001Cancer symptom: apetite_loss
    3008Cancer symptom: clubbing
    3009Cancer symptom: constipation
    3010Cancer symptom: cough
    3011Cancer symptom: diarrhoea
    3012Cancer symptom: distension
    3015Cancer symptom: dysphagia
    3016Cancer symptom: dysuria
    3017Cancer symptom: fatigue
    3019Cancer symptom: haematuria
    3020Cancer symptom: hoarse
    3021Cancer symptom: ida
    3022Cancer symptom: infectrecur
    3023Cancer symptom: jaundice
    3024Cancer symptom: lumpbreast
    3026Cancer symptom: lymphaden
    3027Cancer symptom: lymphaneck
    3028Cancer symptom: massabdo
    3032Cancer test: ca125
    3034Cancer symptom: painabdom
    3035Cancer symptom: painback
    3036Cancer symptom: painbone
    3038Cancer symptom: painupabdo
    3040Cancer symptom: reflux
    3041Cancer symptom: sob
    3042Cancer symptom: splenomegaly
    3045Cancer symptom: weight_loss
    3047Cancer test: ca125
    3051Cancer test: CTPelvis
    3058Cancer test: serumprotein_electro
    3061Cancer groups: oesophagus
    3062Cancer groups: stomach
    3064Cancer groups: colon
    3066Cancer groups: anal
    3067Cancer groups: hepato
    3068Cancer groups: gallbladder
    3070Cancer groups: pancreas
    3071Cancer groups: peritoneum
    3072Cancer groups: lung
    3075Cancer groups: osteo
    3076Cancer groups: melanoma
    3078Cancer groups: breast
    3079Cancer groups: vulval
    3080Cancer groups: cervical
    3081Cancer groups: endometrial
    3082Cancer groups: ovarian
    3083Cancer groups: choriocarcinoma
    3084Cancer groups: penis
    3086Cancer groups: testicular
    3087Cancer groups: spermatic cord
    3088Cancer groups: renal
    3089Cancer groups: bladder
    3090Cancer groups: eye
    3095Cancer groups: secondary_malignancy
    3098Cancer groups: myeloma
    4002Cancer test: CTHead
    4004Cancer test: CT_abdo
    4005Cancer test: CTscan_AllSites
    4006Cancer test: CT_chest
    4007Cancer groups: CNSwho_meningioma_all
    4008Cancer groups: CNSwho_meningioma_I
    4009Cancer groups: CNSwho_meningioma_II
    4010Cancer groups: CNSwho_meningioma_III
    4011Cancer groups: CNSwho_AstrocyticOligodendroglial
    4012Cancer groups: CNSwho_Embryonal
    4013Cancer groups: CNSwho_TumoursSpinalParaspinalNerves
    4014Cancer groups: CNSwho_Pineal
    4015Cancer groups: CNSwho_Ependymoma
    4016Cancer groups: CNSwho_ChoroidPlexus
    4017Cancer groups: CNSwho_mesenchymal
    4018Cancer groups: CNSwho_SellarRegion
    4019Cancer groups: CNSwho_Neuronal_MixedNeuronalGlial
    4020Cancer groups: EyeAndOrbit_total
    4022Cancer test: SerumLDH
    4023Cancer test: brain_MRI_normal
    4024Cancer test: brain_MRI_abnormal
    4025Cancer test: CT_resultAbnormal
    4026Cancer test: CT_resultNormal
    4027Cancer test: chest_xray_normal
    4028Cancer test: chest_xray_abnormal
    4029Cancer test: PSA_result_Abormal
    4030Cancer test: PSA_result_Normal
    4031Cancer test: PSA_result_ObEntity
    4032Cancer test: ca125_procedure
    4033Cancer test: Serumprotein_electro_procedure
    4034Cancer test: USSabdo_Abnormal
    4035Cancer test: USSabdo_Normal
    4036Cancer test: USSpelvis
    4037Cancer test: mammogram
    4038Cancer test: mammogram_result_Normal
    4039Cancer test: mammogram_result_Abnormal
    4040Cancer groups: Stage WHOcns_I
    4041Cancer groups: Stage WHOcns_II
    4042Cancer groups: Stage WHOcns_III
    4043Cancer groups: Stage WHOcns_IV
    4044Cancer groups: Stage TNM_ObEntity
    4045Cancer groups: Small_Intestine_primary
    4046Cancer groups: Small_Intestine_total
    4047Cancer groups: rectum_total
    4048Cancer groups: rectum_InSitu
    4049Cancer test: WhiteCellCount_procedure
    4050Cancer test: WhiteCellCount_ObEntity
    4051Cancer test: LymphocyteCount_procedure
    4052Cancer test: lymphocyteCount_ObEntity
    4053Cancer test: platelets_procedure
    4054Cancer test: platelets_ObEntity
    4055Cancer test: CRP_procedure
    4056Cancer test: CRP_ObEntity
    4057Cancer test: ESR_procedure
    4058Cancer test: ESR_ObEntity
    4059Diagnosis: Death_QualValue
    4060Cancer test: colonoscopy_result_abnormal
    4061Cancer test: colonoscopy_result_normal
    4062Cancer test: sigmoidoscopy
    4063Cancer test: sigmoidoscopy_result_abnormal
    4064Cancer test: sigmoidoscopy_result_normal

    Surveillance & acute pathways of care theme

    General inclusions/exclusions and population covariates:

    • People will be included in cohorts who have a least one year’s historic data in their records.
    • Age will be represented as year or birth
    • Ethnicity will be listed in five categories (we can conduct multiple imputation for missing data)
    • IMD provided at LSOA level to individual records, derived from postcode. Where missing we substitute the practice cohort. Plus provided in quintiles (quintile 1 most deprived)
    • Household size (N.B. Relies on identical address & registered with same practice)
    • Urban, town and city, conurbation (ONS population density)
    • NHS Region – North, Midlands and East, South and London.
    • Registration will be full registration and not include temporary residents
    • We will include a practice indicator
    • We will exclude records where: no valid age or gender, no agreement to share data (approx. 0.2%)
    RAG statusIDCategoryVariableVariable TypeOutputCommentsAvailable for extraction?
    1001PHENOTYPESymptoms involving musculoskeletal
    1003PHENOTYPELaryngitis and Tracheitis
    1005PHENOTYPEStrep Throat and Peritonsillar Abscess
    1006PHENOTYPEIntestinal Infectious Diseases
    1007PHENOTYPEUpper Respiratory Tract InfectionsCase finding
    1008PHENOTYPEAsthmaCase finding
    1011PHENOTYPEChickenpoxCase finding
    1018PHENOTYPEOtitis Media Acute
    1020PHENOTYPEInfluenza-like illnessCase finding
    1021PHENOTYPERubellaCase finding
    1022PHENOTYPERespiratory System Diseases
    1028PHENOTYPESymptoms involving Respiratory and Chest
    1030PHENOTYPEMumpsCase finding
    1031PHENOTYPEImpetigo
    1035PHENOTYPEConjunctival Disorders
    1036PHENOTYPEPleurisy
    1037PHENOTYPEHerpes Simplex
    1038PHENOTYPESymptoms involving Skin and Integument Tissues
    1042PHENOTYPEScabiesCase finding
    1044PHENOTYPEWhooping Cough
    1045PHENOTYPEMeningitis and Encephalitis
    1046PHENOTYPEUrinary Tract Infections
    1048PHENOTYPENon-infective Enteritis and ColitisCase finding
    1052PHENOTYPEPneumonia and PneumonitisCase finding
    1054PHENOTYPESinusitisCase finding
    1055PHENOTYPELower Respiratory Tract InfectionsCase finding
    1056PHENOTYPEViral Hepatitis
    1057PHENOTYPEAllergic RhinitisCase finding
    1058PHENOTYPEBronchitisCase finding
    1060PHENOTYPEHerpes Zoster
    1061PHENOTYPEInfectious Mononucleosis
    1062PHENOTYPESkin and Subcutaneous Tissue Infections
    1063PHENOTYPETonsillitis and acute Pharyngitis
    1066PHENOTYPEPeripheral Nervous Disease
    1067PHENOTYPEBullous Dermatoses
    1068PHENOTYPEMeaslesCase finding
    1001PHENOTYPESymptoms involving musculoskeletal
    1003PHENOTYPELaryngitis and TracheitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1005PHENOTYPEStrep Throat and Peritonsillar AbscessCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1006PHENOTYPEIntestinal Infectious Diseases
    1007PHENOTYPEUpper Respiratory Tract InfectionsCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1008PHENOTYPEAsthmaCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1011PHENOTYPEChickenpoxCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1018PHENOTYPEOtitis Media Acute
    1020PHENOTYPEInfluenza-like illnessCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1021PHENOTYPERubellaCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1022PHENOTYPERespiratory System DiseasesCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1028PHENOTYPESymptoms involving Respiratory and ChestDichotomousFor weekly reports. Based specifically on ICD R05-R07, R09
    1030PHENOTYPEMumpsCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1031PHENOTYPEImpetigo
    1035PHENOTYPEConjunctival DisordersCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1036PHENOTYPEPleurisy
    1037PHENOTYPEHerpes Simplex
    1038PHENOTYPESymptoms involving Skin and Integument Tissues
    1042PHENOTYPEScabiesCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1044PHENOTYPEWhooping Cough
    1045PHENOTYPEMeningitis and EncephalitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1046PHENOTYPEUrinary Tract Infections
    1048PHENOTYPENon-infective Enteritis and ColitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1052PHENOTYPEPneumonia and PneumonitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1054PHENOTYPESinusitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1055PHENOTYPELower Respiratory Tract InfectionsCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1056PHENOTYPEViral Hepatitis
    1057PHENOTYPEAllergic RhinitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1058PHENOTYPEBronchitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1060PHENOTYPEHerpes Zoster
    1061PHENOTYPEInfectious Mononucleosis
    1062PHENOTYPESkin and Subcutaneous Tissue InfectionsCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1063PHENOTYPETonsillitis and acute Pharyngitis
    1066PHENOTYPEPeripheral Nervous Disease
    1067PHENOTYPEBullous DermatosesCase findingDichotomousFor weekly reports. Excludes simple blisters traumatic and otherwise. Limited to concepts with disorder semantic tag
    1068PHENOTYPEMeaslesCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    4180EXPOSUREInfluenzaVaccinesPrescribableWithinGPQOFDrug VaccinationDichotomousdm+d codes. Taken from QOF RefsetID 12465201000001105
    4182EXPOSUREInfluenza vaccination administered by third partyVaccinationDichotomousAdministration codes
    4183EXPOSUREInfluenza vaccination administeredVaccinationDichotomousAdministration codes
    4186EXPOSUREFlu vac 20: QIVe: Sanofi PasteurDrug VaccinationDichotomousdm+d codes
    4187EXPOSUREFlu vac 20: LAIV: AstraZeneca - Fluenz TetraDrug VaccinationDichotomousdm+d codes
    4188EXPOSUREFlu vac 20: QIVe: GSK - Fluarix TetraDrug VaccinationDichotomousdm+d codes
    4189EXPOSUREFlu vac 20: QIVe: Mylan - Influenza Vacc Tetra MYLDrug VaccinationDichotomousdm+d codes
    4190EXPOSUREFlu vac 20: QIVe: Mylan - Influvac sub-unitDrug VaccinationDichotomousdm+d codes
    4191EXPOSUREFlu vac 20: QIVc: Seqirus - Flucelvax TetraDrug VaccinationDichotomousdm+d codes
    4192EXPOSUREFlu vac 20: aTIV: Seqirus - FluadDrug VaccinationDichotomousdm+d codes
    4193EXPOSUREFlu vac 20: TIV-HD: Sanofi PasteurDrug VaccinationDichotomousdm+d codes
    4194EXPOSUREFlu vac 20: QIVe: MASTADrug VaccinationDichotomousdm+d codes
    4198EXPOSUREFlu vac 20: aTIV: GenericDrug VaccinationDichotomousdm+d codes
    4202OUTCOMEInfluenza vaccination declinedVaccinationDichotomousAdmin codes
    4203OUTCOMEInfluenza vaccination DNAVaccinationDichotomousAdmin codes

    Mental Health Theme

    General inclusions/exclusions and population covariates:

    • People will be included in cohorts who have a least one year’s historic data in their records.
    • Age will be represented as year or birth
    • Ethnicity will be listed in five categories (we can conduct multiple imputation for missing data)
    • IMD provided at LSOA level to individual records, derived from postcode. Where missing we substitute the practice cohort. Plus provided in quintiles (quintile 1 most deprived)
    • Household size (N.B. Relies on identical address & registered with same practice)
    • Urban, town and city, conurbation (ONS population density)
    • NHS Region – North, Midlands and East, South and London.
    • Registration will be full registration and not include temporary residents
    • We will include a practice indicator
    • We will exclude records where: no valid age or gender, no agreement to share data (approx. 0.2%)
    Mental Health Theme Template(Nexus 365 access required)