Using Oxford-RCGP RSC for observational studies

Image Image Image

Using Oxford-RCGP RSC for observational studies

The Oxford-RCGP RSC has a current membership of over 1600 general practices in England covering approximately 8 million patients who are broadly representative of the English general population. The emergent COVID-19 pandemic has seen a rapid increase in the number of new practices joining the network to support the national surveillance program. The Oxford-RCGP RSC team transforms routine clinical data from individual patient records at practice level into an accessible repository of data for health research. Data is transformed to series of themed datasets readily available research. These datasets include standard RSC population configuration (based on age band, ethnicity, index of multiple deprivation, and rurality), clinical case definitions (generally ontological), covariates, and outcomes. These are benchmarked to ONS standard populations to enable rapid comparisons between the study and national populations.

How to access RCGP RSC data

RCGP RSC data is available for researchers interested in conducting primary care/ linked data studies. To work with us, please download and complete the data request form (below) and email  to MedicalDirectorRSC@rcgp.org.uk.

We would also need :

  • a protocol, clearly defining the purpose of the request and use of data
  • a list of variables (no abbreviations for the medical terms)
  • ethics approval (evidence if such is not needed – for what evidence you can present, please refer to the guidance notes on the form).

Once processed the request is assigned a reference number and added to the log. It is then scheduled for consideration at the weekly technical meeting and monthly RSC Operational meeting. The official approval happens at the fourth Wednesday of each month when the RCGP RSC operational meeting is held.

    Data request form

    Oxford-RCGP RSC Theme datasets

    The Oxford-RCGP RSC team is developing a series of themed datasets that will allow researchers rapid access to theme specific datasets that can be used for research studies. We offer standard protocols that can be modified to cater to the needs of specific research studies. These datasets can be linked to other data sources and prepared according a data structure that fits the analytical requirements of  the proposed study.

    Our currently planned themes (at different stages of development) are given below. Explore our theme datasets which are ready for research studies by clicking on the buttons on the right.

    Image

    How we develop phenotypes and ontologies to support theme datasets
    We start theme development by forming a group of theme experts led by a theme lead. The theme lead will design the theme dataset based on the common requirements for the research theme. The theme lead populates a theme template based on expert knowledge (or study requirement, if the theme is initially focused on producing a dataset for a study). The theme lead then works with a team of code curators to convert the data requirements of a in to a clinical code specification. This is carried out as a two stage approach (click on the links on the right to learn more). The outputs of the code curation process are stored in a code repository in the secure environment. The codes committed to the code repository are immediately available to be used for data extraction. The code repository is capable of updating automatically to reflect to most code changes in future SNOMED CT releases.
    Image

    Systems involved in the theme development process
    Image

    SNOMED CT Code Tool

    Theme leads and clinicians (with expertise in the theme)  use the SNOMED CT code tool developed by the Oxford-RCGP RSC team to curate variables/codes within each theme.

    Image

    Cardiovascular & Diabetes Theme

    General inclusions/exclusions and population covariates:

    • People will be included in cohorts who have a least one year’s historic data in their records.
    • Age will be represented as year or birth
    • Ethnicity will be listed in five categories (we can conduct multiple imputation for missing data)
    • IMD provided at LSOA level to individual records, derived from postcode. Where missing we substitute the practice cohort. Plus provided in quintiles (quintile 1 most deprived)
    • Household size (N.B. Relies on identical address & registered with same practice)
    • Urban, town and city, conurbation (ONS population density)
    • NHS Region – North, Midlands and East, South and London.
    • Registration will be full registration and not include temporary residents
    • We will include a practice indicator
    • We will exclude records where: no valid age or gender, no agreement to share data (approx. 0.2%)
    CVD Theme Template(Nexus 365 access required)
    RAGConditionIDCategoryConditionNameVariableTypeOutputTypeCommentAvailable
    2044PHENOTYPETIA
    2064PHENOTYPEAsthmaDiagnosis
    95PHENOTYPEChronic Kidney Disease
    1500INVESTGATIONeGFR
    2065EXPOSUREActiveSmoker
    2066EXPOSUREEx-smoker
    2018PHENOTYPEAcuteMyocardialInfarctionCase findingDichotomousStrong evidence of myocardial infarct ever - not just acute
    2011PHENOTYPEIschaemicStroke
    2050INVESTGATIONHbA1c
    1512INVESTGATIONCRP_normal
    1513INVESTGATIONCRP_numeric
    1514INVESTGATIONLFT_ALT
    1516INVESTGATIONDMARD
    1517INVESTGATIONAntiCoagMonitor
    1518INVESTGATIONINRMonitor_num
    1519OUTCOMECOVID-19Shielded
    1515INVESTGATIONLFT_AST
    1520EXPOSURETemperature
    2047PHENOTYPEDiabetes T1
    2048PHENOTYPEDiabetes T2
    2046INVESTGATIONRandom Blood Glucose
    2049INVESTGATIONFasting Blood Glucose
    1522INVESTGATIONHbA1c_IFCC
    1523INVESTGATIONHbA1c_DCCT
    1524INVESTGATIONHbA1c_Unspecified
    1525PHENOTYPEPeriphVascDiseaseLeg
    1526PHENOTYPEChronicLungDisease
    1521EXPOSUREFever
    2067EXPOSURENon-Smoker
    2010PHENOTYPEHypertension
    2054INVESTGATIONHDL cholesterol
    2055INVESTGATIONLDL cholesterol
    2041PHENOTYPERheumatoidArthritis
    1511INVESTGATIONCRP_elevated
    2021PHENOTYPEAngina
    100EXPOSUREBody Mass Index
    2031PHENOTYPECongestiveCardiacFailure
    105EXPOSUREHeight
    2056INVESTGATIONTotal cholesterol
    2148INVESTGATIONCreatinine
    1510OUTCOMECOVID-19TimeICU
    2051EXPOSUREBlood Pressure - Both
    2052EXPOSUREBlood Pressure - Diastolic
    2053EXPOSUREBlood Pressure - Systolic
    2147PHENOTYPEChronic Kidney Disease - Stages 3 to 5
    2133PHENOTYPECOPDDiagnosis
    2126COPDProcessOfCare
    2149INVESTGATIONPCR
    2008PHENOTYPEHaemorrhagicStroke
    2144INVESTGATIONACR
    2025PHENOTYPEAtrialFibrillation
    2045PHENOTYPEUnstableAngina
    110EXPOSUREWeight
    1501INVESTGATIONPlateletCount
    1502INVESTGATIONBMICat_normal
    3160PHENOTYPEIschemicHeartDiseaseJS
    4580OUTCOMEFindingOfDecreaseInAppetiteCase findingDichotomousCurated for use as Adverse Event Indicator
    1503INVESTGATIONBMICat_obese
    1504INVESTGATIONBMICat_Overwt
    1505INVESTGATIONBMICat_Severeobesity
    1506OUTCOMECOVID19HospDisch
    1507OUTCOMECOVID-19HospAttempt
    1508OUTCOMECOVID-19MechVent
    1509OUTCOMECOVID-19OxygenRxAttempt
    4204OUTCOMEAsthmaExacerbationCase findingDichotomous
    4210EXPOSUREAsthmaManagementNoPlanCase findingDichotomous
    4208EXPOSUREAsthmaReviewCase findingDichotomous
    4209EXPOSUREAsthmaManagementPlanCase findingDichotomous
    4660OUTCOMEFindingOfHaemolysisCase findingDichotomousCurated for use as Adverse Event Indicator
    4661OUTCOMEHaemolyticAnaemiaCase findingDichotomousCurated for use as Adverse Event Indicator
    4662OUTCOMEAgranulocytosisCase findingDichotomousCurated for use as Adverse Event Indicator
    4663OUTCOMEAplasticAnaemiaCase findingDichotomousCurated for use as Adverse Event Indicator
    4664OUTCOMEBoneMarrowDepressionCase findingDichotomousCurated for use as Adverse Event Indicator
    4665OUTCOMEFindingOfLeucopeniaCase findingDichotomousCurated for use as Adverse Event Indicator
    4666OUTCOMEFindingOfNeutropeniaCase findingDichotomousCurated for use as Adverse Event Indicator
    4667OUTCOMEThrombocytopenicDisorderCase findingDichotomousCurated for use as Adverse Event Indicator
    4668OUTCOMEStevens-JohnsonSyndromeCase findingDichotomousCurated for use as Adverse Event Indicator
    4669OUTCOMELyellSyndromeCase findingDichotomousCurated for use as Adverse Event Indicator
    4670OUTCOMEDrugReactionWithEosinophiliaAndSystemicSymptomsCase findingDichotomousCurated for use as Adverse Event Indicator
    4671OUTCOMEErythemaMultiformeCase findingDichotomousCurated for use as Adverse Event Indicator
    4672OUTCOMEItchingOfSkinCase findingDichotomousCurated for use as Adverse Event Indicator
    4673OUTCOMEHenoch-SchonleinPurpuraCase findingDichotomousCurated for use as Adverse Event Indicator
    4674OUTCOMEToxicLiverDiseaseCase findingDichotomousCurated for use as Adverse Event Indicator
    4675OUTCOMEChoestaticJaundiceSyndromeCase findingDichotomousCurated for use as Adverse Event Indicator
    4676OUTCOMEHepaticFailureCase findingDichotomousCurated for use as Adverse Event Indicator
    4677OUTCOMEFindingOfAbdominalPainCase findingDichotomousCurated for use as Adverse Event Indicator
    4678OUTCOMEClostridiumDifficileDiarrhoeaCase findingDichotomousCurated for use as Adverse Event Indicator
    4679OUTCOMEPancreatitisCase findingDichotomousCurated for use as Adverse Event Indicator
    4680OUTCOMEOesophagitisCase findingDichotomousCurated for use as Adverse Event Indicator
    4681OUTCOMEUlcerOfOesphagusCase findingDichotomousCurated for use as Adverse Event Indicator
    4682OUTCOMEAngioedemaCase findingDichotomousCurated for use as Adverse Event Indicator
    4683OUTCOMEFindingOfCloudedConsciousnessCase findingDichotomousCurated for use as Adverse Event Indicator
    4684OUTCOMEDeliriumCase findingDichotomousCurated for use as Adverse Event Indicator
    4685OUTCOMEFindingOfExtraPyramidalMovementsCase findingDichotomousCurated for use as Adverse Event Indicator
    4686OUTCOMEFindingOfHallucinationsCase findingDichotomousCurated for use as Adverse Event Indicator
    4687OUTCOMEFindingOfPsychomotorAgitationCase findingDichotomousCurated for use as Adverse Event Indicator
    4688OUTCOMEBenignIntracranialHypertensionCase findingDichotomousCurated for use as Adverse Event Indicator
    4689OUTCOMEFindingOfTinnitusCase findingDichotomousCurated for use as Adverse Event Indicator
    4690OUTCOMEBacterialVaginosisCase findingDichotomousCurated for use as Adverse Event Indicator
    4691OUTCOMEPericarditisCase findingDichotomousCurated for use as Adverse Event Indicator
    4581OUTCOMEFindingOfDiarrhoeaCase findingDichotomousCurated for use as Adverse Event Indicator
    4582OUTCOMEFindingOfNauseaCase findingDichotomousCurated for use as Adverse Event Indicator
    4205EXPOSUREAsthmaPrescribedInhaledCorticosteriods
    4583OUTCOMEFindingOfVomitingCase findingDichotomousCurated for use as Adverse Event Indicator
    4588OUTCOMEFindingOfHeadacheCase findingDichotomousCurated for use as Adverse Event Indicator
    4608OUTCOMEAnaphylaxisCase findingDichotomousCurated for use as Adverse Event Indicator
    4206EXPOSUREAsthmaPrescribedOralCorticosteriods
    4207OUTCOMEAccidentAndEmergencyDepartmentAttended

    Cancer Theme

    General inclusions/exclusions and population covariates:

    • People will be included in cohorts who have a least one year’s historic data in their records.
    • Age will be represented as year or birth
    • Ethnicity will be listed in five categories (we can conduct multiple imputation for missing data)
    • IMD provided at LSOA level to individual records, derived from postcode. Where missing we substitute the practice cohort. Plus provided in quintiles (quintile 1 most deprived)
    • Household size (N.B. Relies on identical address & registered with same practice)
    • Urban, town and city, conurbation (ONS population density)
    • NHS Region – North, Midlands and East, South and London.
    • Registration will be full registration and not include temporary residents
    • We will include a practice indicator
    • We will exclude records where: no valid age or gender, no agreement to share data (approx. 0.2%)
    Cancer Theme Template(Nexus 365 access required)
    RAGConditionIDCategoryConditionNameVariableTypeOutputTypeCommentAvailable
    G4204PHENOTYPEAsthmaExacerbationCase findingDichotomous
    G4210PHENOTYPEAsthmaManagementNoPlanCase findingDichotomous
    G4209PHENOTYPEAsthmaManagementPlanCase findingDichotomous
    G4208PHENOTYPEAsthmaReviewCase findingDichotomous
    G1509COVID-19OxygenRxAttempt
    G1508COVID-19MechVent
    G1507COVID-19HospAttempt
    G1506COVID19HospDisch
    G1505BMICat_Severeobesity
    G1504BMICat_Overwt
    G1503BMICat_obese
    4006cancer_tests_CT_chest
    4004cancer_tests_CT_abdo
    3051cancer_tests_CTPelvis
    4005cancer_tests_CTscan_AllSites
    4022cancer_tests_SerumLDH
    4020PHENOTYPEcancer_groups_EyeAndOrbit_total
    3090PHENOTYPEcancer_groups_eye
    4019PHENOTYPEcancer_groups_CNSwho_Neuronal_MixedNeuronalGlial
    4015PHENOTYPEcancer_groups_CNSwho_Ependymoma
    4014PHENOTYPEcancer_groups_CNSwho_Pineal
    4013PHENOTYPEcancer_groups_CNSwho_TumoursSpinalParaspinalNerves
    4010PHENOTYPEcancer_groups_CNSwho_meningioma_III
    4008PHENOTYPEcancer_groups_CNSwho_meningioma_I
    4002cancer_tests_CTHead
    G1502BMICat_normal
    G1501PlateletCount
    G110Weight
    G2008HaemorrhagicStroke
    G1510COVID-19TimeICU
    1530PHENOTYPEcancer_groups_colon_total
    3076PHENOTYPEcancer_groups_melanoma
    3061PHENOTYPEcancer_groups_oesophagus
    1535PHENOTYPEcancer_groups_pancreas_InSitu
    3001cancer_symptoms_apetite_loss
    3015cancer_symptoms_dysphagia
    3045cancer_symptoms_weight_loss
    3042cancer_symptoms_splenomegaly
    3000cancer_2ww_referrals_
    1541cancer_2ww_referrals_urol
    1542cancer_2ww_referrals_UpperGI
    1543cancer_2ww_referrals_Skin
    1544cancer_2ww_referrals_Sarcoma
    1545cancer_2ww_referrals_Lung
    1546cancer_2ww_referrals_HeadNeck
    1547cancer_2ww_referrals_HaemMalig
    1548cancer_2ww_referrals_Gynae
    1549cancer_2ww_referrals_Colorectal
    1550cancer_2ww_referrals_Breast
    1551cancer_2ww_referrals_LowerGI
    1552cancer_2ww_referrals_Braincancer
    1553PHENOTYPEcancer_groups_bladder_InSitu
    3089PHENOTYPEcancer_groups_bladder
    1554PHENOTYPEcancer_groups_bladder_Total
    3083PHENOTYPEcancer_groups_choriocarcinoma
    1555PHENOTYPEcancer_groups_prostateCa_InSitu
    1556PHENOTYPEcancer_groups_prostateCa_Total
    1557PHENOTYPEcancer_groups_prostateCa_Primary
    1558PHENOTYPEcancer_groups_ovarian_total
    3082PHENOTYPEcancer_groups_ovarian
    1559PHENOTYPEcancer_groups_endometrial_InSitu
    1560PHENOTYPEcancer_groups_endometrial_total
    3081PHENOTYPEcancer_groups_endometrial
    3079PHENOTYPEcancer_groups_vulval
    3047cancer_tests_ca125
    3032cancer_symptoms_nausea
    3027cancer_symptoms_lymphaneck
    4018PHENOTYPEcancer_groups_CNSwho_SellarRegion
    4012PHENOTYPEcancer_groups_CNSwho_Embryonal
    4064cancer_tests_sigmoidoscopy_result_normal
    4063cancer_tests_sigmoidoscopy_result_abnormal
    4062cancer_tests_sigmoidoscopy
    4058cancer_tests_ESR_ObEntity
    4057cancer_tests_ESR_procedure
    4054cancer_tests_platelets_ObEntity
    4053cancer_tests_platelets_procedure
    4050cancer_tests_WhiteCellCount_ObEntity
    4052cancer_tests_lymphocyteCount_ObEntity
    4051cancer_tests_LymphocyteCount_procedure
    4049cancer_tests_WhiteCellCount_procedure
    4047cancer_groups_rectumJS_total
    4046cancer_groups_Small_Intestine_total
    4043cancer_groups_stage_WHOcns_IV
    4041cancer_groups_stage_WHOcns_II
    4040cancer_groups_stage_WHOcns_I
    4059DiagnosisDeath_QualValue
    4039cancer_tests_mammogram_result_Abnormal
    4037cancer_tests_mammogram
    4036cancer_tests_USSpelvis
    4035cancer_tests_USSabdoJS_Normal
    3059cancer_tests_USSabdo
    4030cancer_tests_PSAJS_result_Normal
    4028cancer_tests_chest_xrayJS_abnormal
    4026cancer_tests_CT_resultNormal
    4024cancer_tests_brain_MRIJS_abnormal
    3046cancer_tests_brain_MRI
    4177cancer_tests_colposcopy_abnormal
    4178cancer_tests_colposcopy_normal
    4176cancer_tests_colposcopy_procedure
    4175cancer_tests_PapSmear_result_abnormal
    4170cancer_tests_HPVTest_result_positive
    4167cancer_screen_breast_DNA_DidNotRespond
    4163cancer_screen_breast_MRI_procedure
    4164cancer_screen_breast_mammogram_procedure
    4158cancer_screen_bowel_sigmoidoscopy_FurtherInvest
    4160cancer_screen_bowel_sigmoidoscopy_normal
    4155cancer_screen_bowel_DNA_DidNotRespond
    4145cancer_tests_FOB_procedure_NonScreening
    4152cancer_screen_bowel_FIT_normal
    4146cancer_screen_bowel_FIT_result_ObEntity
    4143cancer_tests_FOB_NonScreening_result_normal
    4135cancer_tests_cystoscopy_procedure
    4127cancer_tests_MCV_ObEntity
    4126cancer_tests_MCV_procedure
    4061cancer_tests_colonoscopy_result_normal
    3049cancer_tests_colonoscopy
    4060cancer_tests_colonoscopy_result_abnormal
    4056cancer_tests_CRP_ObEntity
    4055cancer_tests_CRP_procedure
    4048cancer_groups_rectum_InSitu
    4044cancer_groups_stage_TNM_ObEntity
    4042cancer_groups_stage_WHOcns_III
    4038cancer_tests_mammogram_result_Normal
    4034cancer_tests_USSabdoJS_Abnormal
    4032cancer_tests_ca125JS_procedure
    4031cancer_tests_PSAJS_result_ObEntity
    4029cancer_tests_PSAJS_result_Abormal
    3057cancer_tests_PSA
    4027cancer_tests_chest_xrayJS_normal
    3048cancer_tests_chest_xray
    4025cancer_tests_CT_resultAbnormal
    4023cancer_tests_brain_MRIJS_normal
    4174cancer_tests_PapSmear_result_normal
    4173cancer_tests_PapSmear_result_ObEntity
    4172cancer_tests_PapSmear_procedure
    4171cancer_tests_HPVTest_result_negative
    4169cancer_tests_HPVTest_result_ObEntity
    4168cancer_tests_HPVTest_procedure
    4162cancer_diagnosis_BreastCancer_screening
    4166cancer_screen_breast_result_normal
    4165cancer_screen_breast_result_abnormal
    4159cancer_screen_bowel_sigmoidoscopy_cancer_detected
    4153cancer_screen_bowel_FIT_Abnormal
    4144cancer_tests_FOB_NonScreening_result_ObEntity
    4142cancer_tests_FOB_NonScreening_result_abnormal
    4141cancer_screen_bowel_FOB_result_ObEntity
    4140cancer_screen_bowel_FOB_abnormal
    4139cancer_screen_bowel_FOB_normal
    4138cancer_screen_bowel_FOB_procedure
    4137cancer_tests_cystoscopy_result_abnormal
    4136cancer_tests_cystoscopy_result_normal
    4134cancer_tests_OGD_result_abnormal
    4133cancer_tests_OGD_result_normal
    4132cancer_tests_oesophagogastroduodenoscopyOGD
    4131cancer_tests_VitD3_ObEntity
    4130cancer_tests_VitD3_procedure
    4129cancer_tests_MCH_ObEntity
    4128cancer_tests_MCH_procedure
    4125cancer_tests_haemoglobin_ObEntity
    4124cancer_tests_haemoglobin_procedure
    4123cancer_symptoms_MicroscopicHaematuria
    3065cancer_groups_rectum
    4045cancer_groups_Small_Intestine_primary
    4033cancer_tests_serumprotein_electroJS_procedure
    4161cancer_diagnosis_BowelCancer_screening
    4154cancer_screen_bowel_sigmoidoscopy_procedure
    1561PHENOTYPEcancer_groups_renal_InSitu
    1563PHENOTYPEcancer_groups_renal_Total
    1565cancer_symptoms_NonCardiac_Chest_Pain
    1566cancer_symptoms_UrinaryUrgency
    1567cancer_symptoms_UrinaryFrequency
    3022cancer_symptoms_infectrecur
    3021cancer_symptoms_ida
    1571cancer_symptoms_ChangeBowelHabit
    1570PHENOTYPEcancer_groups_T0_pTis_InSitu
    1573PHENOTYPEcancer_groups_FIGO_Stage3
    1575PHENOTYPEcancer_groups_FIGO_Stage1
    1576PHENOTYPEcancer_groups__Stage_M1
    1579PHENOTYPEcancer_groups__Stage_T3
    1580PHENOTYPEcancer_groups__Stage_T2
    1581PHENOTYPEcancer_groups__Stage_T1
    1582PHENOTYPEcancer_groups__Stage_N4
    1587PHENOTYPEcancer_groups__Dukes_A
    1588PHENOTYPEcancer_groups__Dukes_B
    1589PHENOTYPEcancer_groups__Dukes_C
    1590PHENOTYPEcancer_groups__Dukes_D
    3078PHENOTYPEcancer_groups_breast
    1591PHENOTYPEcancer_groups_breast_InSitu
    3072PHENOTYPEcancer_groups_lung
    1593PHENOTYPEcancer_groups_lung_InSitu
    1594PHENOTYPEcancer_groups_lung_Total
    1595PHENOTYPEcancer_symptoms_breast_SkinNippleChanges
    1597PHENOTYPEcancer_symptoms_UrinaryTractInfection
    3011PHENOTYPEcancer_symptoms_diarrhea
    3075PHENOTYPEcancer_groups_osteo
    3084PHENOTYPEcancer_groups_penis
    3067PHENOTYPEcancer_groups_hepato
    1603PHENOTYPEcancer_groups__Leukaemia_Other
    1604PHENOTYPEcancer_groups__Leukaemia_Total_Overarching
    1605PHENOTYPEcancer_groups__Leukaemia_CLL
    1607PHENOTYPEcancer_groups__Leukaemia_ALL
    1608PHENOTYPEcancer_groups__Leukaemia_AML
    1609PHENOTYPEcancer_groups_NonHodgkinsLymphoma
    1610PHENOTYPEcancer_groups_HodgkinsLymphoma
    1612PHENOTYPEcancer_groups_testicular_InSitu
    1613PHENOTYPEcancer_groups_testicular_Total
    3086PHENOTYPEcancer_groups_testicular
    1614diagnosis_basedonDeathCert_Autopsy
    G1614diagnosis_basedonDeathCert_Autopsy
    1615referrals_2ww_AllCancers_seen
    1616referrals_2ww_Urological_seen
    1617referrals_2ww_UpperGI_seen
    1618referrals_2ww_Skin_seen
    1619referrals_2ww_Sarcoma_seen
    1620referrals_2ww_Lung_seen
    1621referrals_2ww_HaemMalig_seen
    1622referrals_2ww_Gynae_seen
    1623referrals_2ww_ColoRectal_seen
    1625referrals_2ww_BrainCancer_seen
    1626referrals_2ww_HeadNeck_seen
    3068PHENOTYPEcancer_groups_gallbladder
    3071PHENOTYPEcancer_groups_peritoneum
    1629PHENOTYPEcancer_groups_peritoneum_Total
    3058PHENOTYPEcancer_tests_serumprotein_electro
    4017PHENOTYPEcancer_groups_CNSwho_mesenchymal
    4016PHENOTYPEcancer_groups_CNSwho_ChoroidPlexus
    4011PHENOTYPEcancer_groups_CNSwho_AstrocyticOligodendroglial
    4007PHENOTYPEcancer_groups_CNSwho_meningioma_all
    4009PHENOTYPEcancer_groups_CNSwho_meningioma_II
    3088PHENOTYPEcancer_groups_renal
    1562cancer_symptoms_Test_Scrotum_Pain
    3035cancer_symptoms_painback
    3012cancer_symptoms_distension
    3010cancer_symptoms_cough
    1564cancer_symptoms_Test_Scrotum_Mass
    1568cancer_symptoms_Nocturia
    1569cancer_symptoms_Retention
    3016cancer_symptoms_dysuria
    3041cancer_symptoms_sob
    1572PHENOTYPEcancer_groups_FIGO_Stage4
    1574PHENOTYPEcancer_groups_FIGO_Stage2
    1577PHENOTYPEcancer_groups__Stage_M0
    1578PHENOTYPEcancer_groups__Stage_T4
    1583PHENOTYPEcancer_groups__Stage_N3
    1584PHENOTYPEcancer_groups__Stage_N2
    1585PHENOTYPEcancer_groups__Stage_N1
    1586PHENOTYPEcancer_groups__Stage_N0
    1596cancer_symptoms_breast_Pain
    1592PHENOTYPEcancer_groups_breast_Total
    3066PHENOTYPEcancer_groups_anal
    1598PHENOTYPEcancer_groups_anal_Total
    1599PHENOTYPEcancer_groups_Bone_Total
    1600PHENOTYPEcancer_groups_penis_total
    1601PHENOTYPEcancer_groups_hepato_InSitu
    1602PHENOTYPEcancer_groups_hepato_Total
    1606PHENOTYPEcancer_groups__Leukaemia_CML
    1611PHENOTYPEcancer_groups_SpermaticCord_Total
    3087PHENOTYPEcancer_groups_spermatic cord
    1624referrals_2ww_Breast_seen
    1627PHENOTYPEcancer_groups_gallbladder_InSitu
    1628PHENOTYPEcancer_groups_gallbladder_Total
    G105Height
    100Body Mass Index
    3070PHENOTYPEcancer_groups_pancreas
    G1511CRP_elevated
    3080cancer_groups_cervical
    3009cancer_symptoms_constipation
    G1521Fever
    1527PHENOTYPEcancer_groups_cervical_InSitu_CIN3
    1528PHENOTYPEcancer_groups_cervical_total
    1529PHENOTYPEcancer_groups_colon_InSitu
    3064PHENOTYPEcancer_groups_colon
    1531PHENOTYPEcancer_groups_melanoma_InSitu
    1532PHENOTYPEcancer_groups_myeloma_MGUS
    3098PHENOTYPEcancer_groups_myeloma
    1533PHENOTYPEcancer_groups_oesophagus_Barretts_InSitu
    1534PHENOTYPEcancer_groups_oesophagus_total
    1536PHENOTYPEcancer_groups_pancreas_total
    3095PHENOTYPEcancer_groups_secondary_malignancy
    3062PHENOTYPEcancer_groups_stomach
    1537PHENOTYPEcancer_groups_stomach_InSitu
    1538PHENOTYPEcancer_groups_stomach_total
    3024cancer_symptoms_lumpbreast
    3008cancer_symptoms_clubbing
    3036cancer_symptoms_painbone
    G1520Temperature
    G1515LFT_AST
    G1519COVID-19Shielded
    G1514LFT_ALT
    G1513CRP_numeric
    G1512CRP_normal
    G2011IschaemicStroke
    G2018AcuteMyocardialInfarctionCase findingDichotomousStrong evidence of myocardial infarct ever - not just acute
    3017cancer_symptoms_fatigue
    3019cancer_symptoms_haematuria
    3020cancer_symptoms_hoarse
    3023cancer_symptoms_jaundice
    3026cancer_symptoms_lymphaden
    3028cancer_symptoms_massabdo
    3038cancer_symptoms_painupabdo
    1539cancer_symptoms_postmenopausal_bleeding
    3040cancer_symptoms_reflux
    1540cancer_symptoms_vaginaldischarge
    3034cancer_symptoms_painabdom

    Surveillance & acute pathways of care theme

    General inclusions/exclusions and population covariates:

    • People will be included in cohorts who have a least one year’s historic data in their records.
    • Age will be represented as year or birth
    • Ethnicity will be listed in five categories (we can conduct multiple imputation for missing data)
    • IMD provided at LSOA level to individual records, derived from postcode. Where missing we substitute the practice cohort. Plus provided in quintiles (quintile 1 most deprived)
    • Household size (N.B. Relies on identical address & registered with same practice)
    • Urban, town and city, conurbation (ONS population density)
    • NHS Region – North, Midlands and East, South and London.
    • Registration will be full registration and not include temporary residents
    • We will include a practice indicator
    • We will exclude records where: no valid age or gender, no agreement to share data (approx. 0.2%)
    RAGConditionIDCategoryConditionNameVariableTypeOutputTypeCommentAvailable
    1031PHENOTYPEImpetigo
    4583OUTCOMEFindingOfVomitingCase findingDichotomousCurated for use as Adverse Event Indicator
    4582OUTCOMEFindingOfNauseaCase findingDichotomousCurated for use as Adverse Event Indicator
    4691OUTCOMEPericarditisCase findingDichotomousCurated for use as Adverse Event Indicator
    4581OUTCOMEFindingOfDiarrhoeaCase findingDichotomousCurated for use as Adverse Event Indicator
    4690OUTCOMEBacterialVaginosisCase findingDichotomousCurated for use as Adverse Event Indicator
    1063PHENOTYPETonsillitis and acute Pharyngitis
    4608OUTCOMEAnaphylaxisCase findingDichotomousCurated for use as Adverse Event Indicator
    4588OUTCOMEFindingOfHeadacheCase findingDichotomousCurated for use as Adverse Event Indicator
    1060PHENOTYPEHerpes Zoster
    1037PHENOTYPEHerpes Simplex
    1046PHENOTYPEUrinary Tract Infections
    1006PHENOTYPEIntestinal Infectious Diseases
    4689OUTCOMEFindingOfTinnitusCase findingDichotomousCurated for use as Adverse Event Indicator
    4688OUTCOMEBenignIntracranialHypertensionCase findingDichotomousCurated for use as Adverse Event Indicator
    4687OUTCOMEFindingOfPsychomotorAgitationCase findingDichotomousCurated for use as Adverse Event Indicator
    4686OUTCOMEFindingOfHallucinationsCase findingDichotomousCurated for use as Adverse Event Indicator
    4685OUTCOMEFindingOfExtraPyramidalMovementsCase findingDichotomousCurated for use as Adverse Event Indicator
    4684OUTCOMEDeliriumCase findingDichotomousCurated for use as Adverse Event Indicator
    4683OUTCOMEFindingOfCloudedConsciousnessCase findingDichotomousCurated for use as Adverse Event Indicator
    4682OUTCOMEAngioedemaCase findingDichotomousCurated for use as Adverse Event Indicator
    4681OUTCOMEUlcerOfOesphagusCase findingDichotomousCurated for use as Adverse Event Indicator
    4680OUTCOMEOesophagitisCase findingDichotomousCurated for use as Adverse Event Indicator
    4679OUTCOMEPancreatitisCase findingDichotomousCurated for use as Adverse Event Indicator
    4678OUTCOMEClostridiumDifficileDiarrhoeaCase findingDichotomousCurated for use as Adverse Event Indicator
    4677OUTCOMEFindingOfAbdominalPainCase findingDichotomousCurated for use as Adverse Event Indicator
    4676OUTCOMEHepaticFailureCase findingDichotomousCurated for use as Adverse Event Indicator
    4675OUTCOMEChoestaticJaundiceSyndromeCase findingDichotomousCurated for use as Adverse Event Indicator
    4674OUTCOMEToxicLiverDiseaseCase findingDichotomousCurated for use as Adverse Event Indicator
    1056PHENOTYPEViral Hepatitis
    1061PHENOTYPEInfectious Mononucleosis
    1066PHENOTYPEPeripheral Nervous Disease
    1044PHENOTYPEWhooping Cough
    1036PHENOTYPEPleurisy
    1001PHENOTYPESymptoms involving musculoskeletal
    1038PHENOTYPESymptoms involving Skin and Integument Tissues
    4182EXPOSUREInfluenza vaccination administered by third partyVaccinationDichotomousAdministration codes
    4183EXPOSUREInfluenza vaccination administeredVaccinationDichotomousAdministration codes
    4186EXPOSUREFlu vac 20: QIVe: Sanofi PasteurDrug VaccinationDichotomousdm+d codes
    4187EXPOSUREFlu vac 20: LAIV: AstraZeneca - Fluenz TetraDrug VaccinationDichotomousdm+d codes
    4188EXPOSUREFlu vac 20: QIVe: GSK - Fluarix TetraDrug VaccinationDichotomousdm+d codes
    4189EXPOSUREFlu vac 20: QIVe: Mylan - Influenza Vacc Tetra MYLDrug VaccinationDichotomousdm+d codes
    4190EXPOSUREFlu vac 20: QIVe: Mylan - Influvac sub-unitDrug VaccinationDichotomousdm+d codes
    4191EXPOSUREFlu vac 20: QIVc: Seqirus - Flucelvax TetraDrug VaccinationDichotomousdm+d codes
    4192EXPOSUREFlu vac 20: aTIV: Seqirus - FluadDrug VaccinationDichotomousdm+d codes
    4193EXPOSUREFlu vac 20: TIV-HD: Sanofi PasteurDrug VaccinationDichotomousdm+d codes
    4194EXPOSUREFlu vac 20: QIVe: MASTADrug VaccinationDichotomousdm+d codes
    4198EXPOSUREFlu vac 20: aTIV: GenericDrug VaccinationDichotomousdm+d codes
    4661OUTCOMEHaemolyticAnaemiaCase findingDichotomousCurated for use as Adverse Event Indicator
    4660OUTCOMEFindingOfHaemolysisCase findingDichotomousCurated for use as Adverse Event Indicator
    4665OUTCOMEFindingOfLeucopeniaCase findingDichotomousCurated for use as Adverse Event Indicator
    4664OUTCOMEBoneMarrowDepressionCase findingDichotomousCurated for use as Adverse Event Indicator
    4663OUTCOMEAplasticAnaemiaCase findingDichotomousCurated for use as Adverse Event Indicator
    4662OUTCOMEAgranulocytosisCase findingDichotomousCurated for use as Adverse Event Indicator
    4673OUTCOMEHenoch-SchonleinPurpuraCase findingDichotomousCurated for use as Adverse Event Indicator
    4672OUTCOMEItchingOfSkinCase findingDichotomousCurated for use as Adverse Event Indicator
    4671OUTCOMEErythemaMultiformeCase findingDichotomousCurated for use as Adverse Event Indicator
    4670OUTCOMEDrugReactionWithEosinophiliaAndSystemicSymptomsCase findingDichotomousCurated for use as Adverse Event Indicator
    4669OUTCOMELyellSyndromeCase findingDichotomousCurated for use as Adverse Event Indicator
    4668OUTCOMEStevens-JohnsonSyndromeCase findingDichotomousCurated for use as Adverse Event Indicator
    4667OUTCOMEThrombocytopenicDisorderCase findingDichotomousCurated for use as Adverse Event Indicator
    4666OUTCOMEFindingOfNeutropeniaCase findingDichotomousCurated for use as Adverse Event Indicator
    4584OUTCOMEFindingOfDrowsinessCase findingDichotomousCurated for use as Adverse Event Indicator
    4585OUTCOMEFindingOfFatigueCase findingDichotomousCurated for use as Adverse Event Indicator
    4586OUTCOMEFindingOfIrritabilityCase findingDichotomousCurated for use as Adverse Event Indicator
    4587OUTCOMEFindingOfMalaiseCase findingDichotomousCurated for use as Adverse Event Indicator
    4589OUTCOMEFindingOfLocalisedErythemaCase findingDichotomousCurated for use as Adverse Event Indicator
    4590OUTCOMEArthropathyCase findingDichotomousCurated for use as Adverse Event Indicator
    4591OUTCOMEFindingOfMyalgiaCase findingDichotomousCurated for use as Adverse Event Indicator
    4592OUTCOMEGuillainBarrieSyndromeCase findingDichotomousCurated for use as Adverse Event Indicator
    4593OUTCOMEFindingOfPeripheralTremorCase findingDichotomousCurated for use as Adverse Event Indicator
    4594OUTCOMESeizureCase findingDichotomousCurated for use as Adverse Event Indicator
    4595OUTCOMEFebrileConvulsionCase findingDichotomousCurated for use as Adverse Event Indicator
    4596OUTCOMEBellsPalsyCase findingDichotomousCurated for use as Adverse Event Indicator
    4597OUTCOMEEruptionOfSkinCase findingDichotomousCurated for use as Adverse Event Indicator
    4598OUTCOMEConjunctivitisCase findingDichotomousCurated for use as Adverse Event Indicator
    4599OUTCOMECommonColdCase findingDichotomousCurated for use as Adverse Event Indicator
    4600OUTCOMEFindingOfCoughCase findingDichotomousCurated for use as Adverse Event Indicator
    4601OUTCOMEBleedingFromNoseCase findingDichotomousCurated for use as Adverse Event Indicator
    4602OUTCOMEFindingOfHoarsenessCase findingDichotomousCurated for use as Adverse Event Indicator
    4603OUTCOMEFindingOfNasalCongestionCase findingDichotomousCurated for use as Adverse Event Indicator
    4604OUTCOMEFindingOfPainfulMouthCase findingDichotomousCurated for use as Adverse Event Indicator
    4605OUTCOMEFindingOfSoreThroatCase findingDichotomousCurated for use as Adverse Event Indicator
    4606OUTCOMEFindingOfNasalDischargeCase findingDichotomousCurated for use as Adverse Event Indicator
    4607OUTCOMEFindingOfWheezingCase findingDichotomousCurated for use as Adverse Event Indicator
    4609OUTCOMEFindingOfOedemaOfFaceCase findingDichotomousCurated for use as Adverse Event Indicator
    4610OUTCOMEHypersensitivityReactionCase findingDichotomousCurated for use as Adverse Event Indicator
    1068PHENOTYPEMeaslesCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1042PHENOTYPEScabiesCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1048PHENOTYPENon-infective Enteritis and ColitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1028PHENOTYPESymptoms involving Respiratory and ChestSymptomDichotomousFor weekly reports. Based specifically on ICD R05-R07, R09
    1054PHENOTYPESinusitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1045PHENOTYPEMeningitis and EncephalitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1022PHENOTYPERespiratory System DiseasesCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1003PHENOTYPELaryngitis and TracheitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1005PHENOTYPEStrep Throat and Peritonsillar AbscessCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1067PHENOTYPEBullous DermatosesCase findingDichotomousFor weekly reports. Excludes simple blisters traumatic and otherwise. Limited to concepts with disorder semantic tag
    1035PHENOTYPEConjunctival DisordersCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    4180EXPOSUREInfluenzaVaccinesPrescribableWithinGPQOFDrug VaccinationDichotomousdm+d codes. Taken from QOF RefsetID 12465201000001105
    1062PHENOTYPESkin and Subcutaneous Tissue InfectionsCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    4202OUTCOMEInfluenza vaccination declinedVaccinationDichotomousAdmin codes
    4203OUTCOMEInfluenza vaccination DNAVaccinationDichotomousAdmin codes
    1018PHENOTYPEOtitis Media AcuteCase findingDichotomousFor weekly reports limited to disorders
    4580OUTCOMEFindingOfDecreaseInAppetiteCase findingDichotomousCurated for use as Adverse Event Indicator
    1058PHENOTYPEBronchitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1020PHENOTYPEInfluenza-like illnessCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1055PHENOTYPELower Respiratory Tract InfectionsCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1007PHENOTYPEUpper Respiratory Tract InfectionsCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1057PHENOTYPEAllergic RhinitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1052PHENOTYPEPneumonia and PneumonitisCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1008PHENOTYPEAsthmaCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1021PHENOTYPERubellaCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1030PHENOTYPEMumpsCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag
    1011PHENOTYPEChickenpoxCase findingDichotomousFor weekly reports. Limited to concepts with disorder semantic tag

    Mental Health Theme

    General inclusions/exclusions and population covariates:

    • People will be included in cohorts who have a least one year’s historic data in their records.
    • Age will be represented as year or birth
    • Ethnicity will be listed in five categories (we can conduct multiple imputation for missing data)
    • IMD provided at LSOA level to individual records, derived from postcode. Where missing we substitute the practice cohort. Plus provided in quintiles (quintile 1 most deprived)
    • Household size (N.B. Relies on identical address & registered with same practice)
    • Urban, town and city, conurbation (ONS population density)
    • NHS Region – North, Midlands and East, South and London.
    • Registration will be full registration and not include temporary residents
    • We will include a practice indicator
    • We will exclude records where: no valid age or gender, no agreement to share data (approx. 0.2%)
    Mental Health Theme Template(Nexus 365 access required)
    RAGConditionIDCategoryConditionNameVariableTypeOutputTypeCommentAvailable
    4179PHENOTYPEAcutePolymorphicPsychoticDisWoSympOfSchizophreniaCase findingDichotomous
    4420PHENOTYPERecurrentManicEpisodesCase findingDichotomous
    4421PHENOTYPEManiaWithPsychoticFeaturesCase findingDichotomous
    4422PHENOTYPEManiaWithMood-congruentPsychoticFeaturesCase findingDichotomous
    4423PHENOTYPEManiaWithMood-incongruentPsychoticFeaturesCase findingDichotomous
    4424PHENOTYPEBipolarIDisorderMostRecentEpisodeHypomanicCase findingDichotomous
    4425PHENOTYPEBipolarAffectiveDisorderCurrentEpisodeManicCase findingDichotomous
    4426PHENOTYPEBipolarAffectiveDisorderCurrentEpisodeDepressionCase findingDichotomous
    4427PHENOTYPEBipolarAffectiveDisorderCurrentEpisodeMixedCase findingDichotomous
    4429PHENOTYPEMildMajorDepressionSingleEpisodeCase findingDichotomous
    4430PHENOTYPEModerateMajorDepressionSingleEpisodeCase findingDichotomous
    4431PHENOTYPEModeratelySevereMajorDepressionSingleEpisodeCase findingDichotomous
    4432PHENOTYPESingleMajorDepressiveEpisodeSevereWithPsychosisCase findingDichotomous
    4433PHENOTYPEMildRecurrentMajorDepressionCase findingDichotomous
    4434PHENOTYPEModerateRecurrentMajorDepressionCase findingDichotomous
    4486PHENOTYPEInhibitedFemaleOrgasmCase findingDichotomous
    4487PHENOTYPEInhibitedMaleOrgasmCase findingDichotomous
    4488PHENOTYPELifelongGeneralisedAnorgasmiaCase findingDichotomous
    4489PHENOTYPELifelongSituationalAnorgasmiaCase findingDichotomous
    4490PHENOTYPELifelongGeneralisedEarlyEjaculationCase findingDichotomous
    4491PHENOTYPELifelongSituationalEarlyEjaculationCase findingDichotomous
    4558PHENOTYPENon-organicContinuousEncopresisCase findingDichotomous
    4559PHENOTYPENon-organicDiscontinuousEncopresisCase findingDichotomous
    4560PHENOTYPEDevelopmentalDelayInFeedingCase findingDichotomous
    4561PHENOTYPENon-organicInfantFeedingDisturbanceCase findingDichotomous
    4566PHENOTYPEIntentionalPoisoningByDrugCase findingDichotomous
    4567PHENOTYPEIntentionalPoisoningCase findingDichotomous
    4568PHENOTYPEIntentionallyHarmingSelfCase findingDichotomous
    4575PHENOTYPEBPDMostRecentEpisodeManicSevereWithPsychosisCase findingDichotomous
    4392PHENOTYPEHarmfulUseOfAlcoholCase findingDichotomous
    4393PHENOTYPEHarmfulUseOfOpioidCase findingDichotomous
    4394PHENOTYPEHarmfulUseOfCannabisCase findingDichotomous
    4395PHENOTYPEHarmfulUseOfSyntheticCannabinoidCase findingDichotomous
    4396PHENOTYPEHarmfulUseOfHypnoticCase findingDichotomous
    4397PHENOTYPEHarmfulUseOfCocaineCase findingDichotomous
    4398PHENOTYPEHarmfulUseOfHallucinogenCase findingDichotomous
    4403PHENOTYPEPost-schizophrenicDepressionCase findingDichotomous
    4613PHENOTYPEDementiaWithEpilepsyCase findingDichotomous
    4614PHENOTYPEFrontotemporalDementiaCase findingDichotomous
    4615PHENOTYPEDementiaWithHepatolenticularDegenerationCase findingDichotomous
    4616PHENOTYPEDementiaDueToHypercalcaemiaCase findingDichotomous
    4618PHENOTYPEDementiaDueToIntoxicationCase findingDichotomous
    4619PHENOTYPEDementiaDueToMultipleSclerosisCase findingDichotomous
    4620PHENOTYPEDementiaDueToNeurosyphilisCase findingDichotomous
    4625PHENOTYPEDementiaDueToTraumaticBrainInjuryCase findingDichotomous
    4628PHENOTYPEAcuteSubacuteBrainSyndromeCase findingDichotomous
    4630PHENOTYPEAcuteSubacuteInfectivePsychosisCase findingDichotomous
    4633PHENOTYPEDeliriumOfMixedEtiologyCase findingDichotomous
    4634PHENOTYPEDeliriumSuperimposedOnDementiaCase findingDichotomous
    4635PHENOTYPESundowningCase findingDichotomous
    4638PHENOTYPEParanoidDisorderCase findingDichotomous
    4639PHENOTYPEParaphreniaCase findingDichotomous
    4640PHENOTYPEAcuteParanoidReactionCase findingDichotomous
    4643PHENOTYPEPremenstrualDysphoricDisorderCase findingDichotomous
    4644PHENOTYPEDisruptiveMoodDysregulationDisorderCase findingDichotomous
    4647PHENOTYPEAndrophobiaCase findingDichotomous
    4648PHENOTYPEGynephobiaCase findingDichotomous
    4649PHENOTYPEAdjustmentDisorderCase findingDichotomous
    4650PHENOTYPEPsychogenicDysmenorrheaCase findingDichotomous
    4651PHENOTYPEPsychogenicDysphagiaCase findingDichotomous
    4652PHENOTYPEPsychogenicPruritisCase findingDichotomous
    4653PHENOTYPEPsychogenicTorticollisCase findingDichotomous
    4654PHENOTYPESomatoformAutonomicDysfunctionCase findingDichotomous
    4655PHENOTYPETeethGrindingCase findingDichotomous
    4656PHENOTYPEPseudobulbarAffectCase findingDichotomous
    4657PHENOTYPENightmareDisorderCase findingDichotomous
    4658PHENOTYPESexualAversionDisorderCase findingDichotomous
    4659PHENOTYPEIntermittentExplosiveDisorderCase findingDichotomous
    4565PHENOTYPEClutteringCase findingDichotomous
    4563PHENOTYPEStereotypyHabitDisorderCase findingDichotomous
    4562PHENOTYPEPicaOfInfancyAndChildhoodCase findingDichotomous
    4557PHENOTYPEUrinaryIncontinenceOfNon-organicOriginCase findingDichotomous
    4564PHENOTYPEStammeringCase findingDichotomous
    4556PHENOTYPEGillesDeLaTourettesSyndromeCase findingDichotomous
    4554PHENOTYPEChronicMotorTicDisorderCase findingDichotomous
    4553PHENOTYPETransientTicDisorderCase findingDichotomous
    4549PHENOTYPESiblingJealousyCase findingDichotomous
    4550PHENOTYPEElectiveMutismCase findingDichotomous
    4551PHENOTYPEReactiveAttachmentDisorderCase findingDichotomous
    4552PHENOTYPEChildhoodDisinhibitedAttachmentDisorderCase findingDichotomous
    4475PHENOTYPEPicaCase findingDichotomous
    4548PHENOTYPEChildhoodPhobicAnxietyDisorderCase findingDichotomous
    4547PHENOTYPESeparationAnxietyDisorderOfChildhoodCase findingDichotomous
    4546PHENOTYPEDepressiveConductDisorderCase findingDichotomous
    4545PHENOTYPEOppositionalDefiantDisorderCase findingDichotomous
    4544PHENOTYPEConductDisorder-UnsocialisedCase findingDichotomous
    4543PHENOTYPESocialisedBehaviourDisorderCase findingDichotomous
    4541PHENOTYPEAttentionDeficitHyperactivityDisorderCase findingDichotomous
    4542PHENOTYPEHyperkineticConductDisorderCase findingDichotomous
    4540PHENOTYPEAspergersDisorderCase findingDichotomous
    4539PHENOTYPERettsDisorderCase findingDichotomous
    4537PHENOTYPEAutisticDisorderOfChildhoodOnsetCase findingDichotomous
    4535PHENOTYPEMixedDisorderOfScholasticSkillsCase findingDichotomous
    4534PHENOTYPEAphasia-angularGyrusSyndromeCase findingDichotomous
    4533PHENOTYPEDyscalculiaCase findingDichotomous
    4532PHENOTYPESpecificSpellingDisorderCase findingDichotomous
    4530PHENOTYPESpecificReadingDisorderCase findingDichotomous
    4529PHENOTYPELispingCase findingDichotomous
    4528PHENOTYPEAcquiredEpilepticAphasiaCase findingDichotomous
    4526PHENOTYPEReceptiveLanguageDisorderCase findingDichotomous
    4524PHENOTYPEExpressiveLanguageDisorderCase findingDichotomous
    4523PHENOTYPEDevelopmentalArticulationDisorderCase findingDichotomous
    4514PHENOTYPEMunchausensSyndromeCase findingDichotomous
    4513PHENOTYPETrichotillomaniaCase findingDichotomous
    4512PHENOTYPEKleptomaniaCase findingDichotomous
    4511PHENOTYPEPyromaniaCase findingDichotomous
    4510PHENOTYPECompulsiveGamblingCase findingDichotomous
    4509PHENOTYPEPsychoneuroticPersonalityDisorderCase findingDichotomous
    4508PHENOTYPEPassiveAggressivePersonalityDisorderCase findingDichotomous
    4507PHENOTYPENarcissisticPersonalityDisorderCase findingDichotomous
    4506PHENOTYPEImmaturePersonalityDisorderCase findingDichotomous
    4505PHENOTYPEEccentricPersonalityDisorderCase findingDichotomous
    4504PHENOTYPEDependentPersonalityDisorderCase findingDichotomous
    4503PHENOTYPEAvoidantPersonalityDisorderCase findingDichotomous
    4502PHENOTYPEObsessiveCompulsivePersonalityDisorderCase findingDichotomous
    4501PHENOTYPEHistrionicPersonalityDisorderCase findingDichotomous
    4500PHENOTYPEEmotionallyUnstablePersonalityDisorderCase findingDichotomous
    4499PHENOTYPEAntisocialPersonalityDisorderCase findingDichotomous
    4498PHENOTYPESchizoidPersonalityDisorderCase findingDichotomous
    4497PHENOTYPEParanoidPersonalityDisorderCase findingDichotomous
    4496PHENOTYPEPostpartumPsychosisCase findingDichotomous
    4495PHENOTYPEPostpartumDepressionCase findingDichotomous
    4494PHENOTYPEExcessiveSexualDriveCase findingDichotomous
    4493PHENOTYPEPsychologicDyspareuniaCase findingDichotomous
    4492PHENOTYPEPsychologicVaginismusCase findingDichotomous
    4485PHENOTYPEPsychogenicImpotenceCase findingDichotomous
    4484PHENOTYPEPrimaryErectileDysfunctionCase findingDichotomous
    4483PHENOTYPEFemaleSexualArousalDisorderCase findingDichotomous
    4482PHENOTYPEAnhedoniaCase findingDichotomous
    4481PHENOTYPELackOrLossOfSexualDesireCase findingDichotomous
    4480PHENOTYPESleepTerrorDisorderCase findingDichotomous
    4479PHENOTYPESleepWalkingDisorderCase findingDichotomous
    4478PHENOTYPENon-organicDisorderOfTheSleep-wakeScheduleCase findingDichotomous
    4477PHENOTYPEPrimaryHypersomniaCase findingDichotomous
    4476PHENOTYPENonorganicInsomniaCase findingDichotomous
    4464PHENOTYPENeurocirculatoryAstheniaCase findingDichotomous
    4465PHENOTYPEPsychalgiaCase findingDichotomous
    4466PHENOTYPEDepersonalisation-derealisationSyndromeCase findingDichotomous
    4467PHENOTYPEDhatCase findingDichotomous
    4468PHENOTYPEPsychasthenicNeurosisCase findingDichotomous
    4469PHENOTYPEPsychogenicSyncopeCase findingDichotomous
    4470PHENOTYPEOccupationalNeurosisCase findingDichotomous
    4471PHENOTYPEAnorexiaNervosaCase findingDichotomous
    4472PHENOTYPEAtypicalAnorexiaNervosaCase findingDichotomous
    4473PHENOTYPEBulimiaNervosaCase findingDichotomous
    4474PHENOTYPEAtypicalBulimiaNervosaCase findingDichotomous
    4448PHENOTYPEPsychogenicAmnesiaCase findingDichotomous
    4449PHENOTYPEPsychogenicFugueCase findingDichotomous
    4450PHENOTYPEDissociativeStuporCase findingDichotomous
    4451PHENOTYPEDissociativeTranceCase findingDichotomous
    4452PHENOTYPEDissociativeMotorDisorderCase findingDichotomous
    4453PHENOTYPEDissociativeConvulsionsCase findingDichotomous
    4454PHENOTYPEDissociativeAnaesthesiaCase findingDichotomous
    4455PHENOTYPEPsychologicConversionDisorderCase findingDichotomous
    4456PHENOTYPEGanserSyndromeCase findingDichotomous
    4457PHENOTYPEMultiplePersonalityDisorderCase findingDichotomous
    4458PHENOTYPEBriquetsSyndromeCase findingDichotomous
    4459PHENOTYPEUndifferentiatedSomatoformDisorderCase findingDichotomous
    4460PHENOTYPEBodyDysmorphicDisorderCase findingDichotomous
    4461PHENOTYPEIllnessAnxietyDisorderCase findingDichotomous
    4462PHENOTYPECutaneousHypochondriasisCase findingDichotomous
    4446PHENOTYPEAcute stress disorderCase findingDichotomous
    4444PHENOTYPEGeneralisedAnxietyDisorderCase findingDichotomous
    4447PHENOTYPEPosttraumaticStressDisorderCase findingDichotomous
    4443PHENOTYPEPanicDisorderCase findingDichotomous
    4435PHENOTYPECyclothymiaCase findingDichotomous
    4436PHENOTYPEDysthymiaCase findingDichotomous
    4437PHENOTYPEAgoraphobiaCase findingDichotomous
    4438PHENOTYPESocialPhobiaCase findingDichotomous
    4439PHENOTYPEAcrophobiaCase findingDichotomous
    4440PHENOTYPEZoophobiaCase findingDichotomous
    4441PHENOTYPEClaustrophobiaCase findingDichotomous
    4442PHENOTYPESimplePhobiaCase findingDichotomous
    4418PHENOTYPEHypomaniaCase findingDichotomous
    4428PHENOTYPEBipolarIIDisorderCase findingDichotomous
    4413PHENOTYPESharedParanoidDisorderCase findingDichotomous
    4414PHENOTYPEInducedPsychoticDisorderCase findingDichotomous
    4416PHENOTYPESchizoaffectiveDisorderDepressiveTypeCase findingDichotomous
    4417PHENOTYPESchizoaffectiveDisorderMixedTypeCase findingDichotomous
    4411PHENOTYPEParanoiaQuerulansCase findingDichotomous
    4410PHENOTYPEInvolutionalParanoidStateCase findingDichotomous
    4409PHENOTYPEDelusionalDysmorphophobiaCase findingDichotomous
    4405PHENOTYPESimpleSchizophreniaCase findingDichotomous
    4404PHENOTYPEResidualSchizophreniaCase findingDichotomous
    4402PHENOTYPEUndifferentiatedSchizophreniaCase findingDichotomous
    4401PHENOTYPECatatonicSchizophreniaCase findingDichotomous
    4400PHENOTYPEDisorganisedSchizophreniaCase findingDichotomous
    4399PHENOTYPEParanoidSchizophreniaCase findingDichotomous
    4370PHENOTYPEDementiaDueToPicksDiseaseCase findingDichotomous
    4371PHENOTYPEDementiaDueToCreutzfeldtJakobDiseaseCase findingDichotomous
    4372PHENOTYPEDementiaDueToHuntingtonChoreaCase findingDichotomous
    4373PHENOTYPEDementiaDueToParkinsonsDiseaseCase findingDichotomous
    4374PHENOTYPEDementiaAssociatedWithAIDSCase findingDichotomous
    4380PHENOTYPEOrganicDissociativeDisorderCase findingDichotomous
    4381PHENOTYPEOrganicEmotionallyLabileDisorderCase findingDichotomous
    4383PHENOTYPEPostencephaliticMyoclonusCase findingDichotomous
    4515PHENOTYPEMildLearningDisabilityCase findingDichotomous
    4517PHENOTYPEModerateLearningDisabilityCase findingDichotomous
    4519PHENOTYPESevereLearningDisabilityCase findingDichotomous
    4521PHENOTYPEProfoundLearningDisabilityCase findingDichotomous
    4385PHENOTYPEAlcoholIntoxicationCase findingDichotomous
    4386PHENOTYPEOpioidIntoxicationCase findingDichotomous
    4387PHENOTYPECannabisIntoxicationCase findingDichotomous
    4388PHENOTYPEHypnoticIntoxicationCase findingDichotomous
    4389PHENOTYPECocaineIntoxicationCase findingDichotomous
    4390PHENOTYPEStimulantIntoxicationCase findingDichotomous
    4391PHENOTYPEHallucinogenIntoxicationCase findingDichotomous
    4412PHENOTYPEAcuteSchizophrenia-likePsychoticDisorderCase findingDichotomous
    4369PHENOTYPEVascularDementiaCase findingDichotomous
    4375PHENOTYPEOrganicHallucinosisCase findingDichotomous
    4376PHENOTYPEOrganicCatatonicDisorderCase findingDichotomous
    4377PHENOTYPEOrganicDelusionalDisorderCase findingDichotomous
    4378PHENOTYPEOrganicMoodDisorderCase findingDichotomous
    4379PHENOTYPEOrganicAnxietyDisorderCase findingDichotomous
    4382PHENOTYPEOrganicPersonalityDisorderCase findingDichotomous
    4384PHENOTYPEPostconcussionSyndromeCase findingDichotomous
    4407PHENOTYPESchizotypalPersonalityDisorderCase findingDichotomous
    4415PHENOTYPESchizoaffectiveDisorderManicTypeCase findingDichotomous
    4419PHENOTYPEManicDisorderSingleEpisodeCase findingDichotomous
    4445PHENOTYPEObsessive-compulsiveDisorderCase findingDichotomous
    4642PHENOTYPEAtypicalDepression
    4576PHENOTYPEPsychosisAndSevereDepressionWithAndDueToBPD
    4617PHENOTYPEDementiaDueToHypothyroidism
    4574PHENOTYPEAcutePolymorphicPsychoticDisWiSympOfSchizophrenia
    4624PHENOTYPEDementiaDueToSLE
    4527PHENOTYPEDevelopmentalReceptiveLanguageDisorder
    4699PHENOTYPEDomesticAbuse
    4636PHENOTYPEVolatileSolventIntoxication
    4627PHENOTYPEDementiaDueToVitaminBDeficiency
    4579PHENOTYPESevereRecurrentMajorDepressionWithPsychoticFeature
    4702PHENOTYPEDomesticAbuseOfAdult
    4645PHENOTYPENaturalEnvironmentTypePhobia
    4516PHENOTYPEMildIntellectualDisability
    4536PHENOTYPEDCD-DevelopmentalCoordinationDisorder
    4622PHENOTYPEDementiaDueToPolyarteritisNodosa
    4611PHENOTYPEDementiaWithLewyBodies
    4631PHENOTYPEAcuteSubacuteOrganicReaction
    4525PHENOTYPEDevelopmentalExpressiveLanguageDisorder
    4522PHENOTYPEProfoundIntellectualDisability
    4577PHENOTYPESevereMajorDepressiveDisWithAnxietySingleEpisode
    4531PHENOTYPEDyslexia
    4408PHENOTYPEDelusionalDisorder
    4700PHENOTYPEDomesticEmotionalAbuse
    4637PHENOTYPEHarmfulUseOfVolatileSolvents
    4518PHENOTYPEModerateIntellectualDisability
    4538PHENOTYPEAtypicalAutism
    4698PHENOTYPEVictimOfAbuse
    4621PHENOTYPEDementiaDueToNiacinDeficiency
    4578PHENOTYPESevereRecurrentMajorDepression
    4555PHENOTYPEVocalTicDisorder
    4701PHENOTYPEDomesticSexualAbuse
    4641PHENOTYPEPyschogenicParanoidPsychosis
    2070PHENOTYPEDomesticViolenceCase findingDichotomous
    4646PHENOTYPEBloodInjuryInjectionTypePhobia
    4612PHENOTYPEDementiaWithParkinsonism
    4632PHENOTYPEAcuteSubacutePsychoOrganicSyndrome
    4623PHENOTYPEDementiaDueToPrionDisease
    4520PHENOTYPESevereIntellectualDisability
    4626PHENOTYPEDementiaDueToTrypanosomiasis
    4406PHENOTYPECoenesthopathicSchizophrenia
    4629PHENOTYPEAcuteSubacuteConfusionalState
    4463PHENOTYPEPsychogenicDyspepsia